Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 18/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717173 | 0.90 | GRM5 (0.47) | GRM5 | |
| SCHEMBL1907392 | 0.90 | GRM5 (0.47) | GRM5 | |
| SCHEMBL3276812 | 0.84 | GRM5 (0.49) | GRM5 | |
| SCHEMBL1899368 | 0.84 | GRM5 (0.49) | GRM5 | |
| SCHEMBL4565316 | 0.83 | GRM5 (0.42) | GRM5 | |
| SCHEMBL992077 | 0.81 | GRM5 (0.44) | GRM5 | |
| SCHEMBL990212 | 0.81 | GRM5 (0.44) | GRM5 | |
| SCHEMBL14734735 | 0.80 | GRM5 (0.44) | GRM5 | |
| SCHEMBL2839746 | 0.79 | GRM5 (0.43) | GRM5 | |
| SCHEMBL2842438 | 0.79 | GRM5 (0.43) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010000763-A2 | COMBINATION PRODUCTS | NOVARTIS AG (CH) | 2010-01-07 | — | — | WO | disclosed |