Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14692665 | 0.67 | — | — | |
| SCHEMBL6227999 | 0.59 | — | — | |
| SCHEMBL6230255 | 0.59 | — | — | |
| SCHEMBL27858841 | 0.56 | CA12 (0.31) | CA12CA1CA2CA7CA14 | |
| SCHEMBL6200437 | 0.52 | — | — | |
| SCHEMBL19284754 | 0.48 | — | — | |
| SCHEMBL202948 | 0.46 | CA2 (0.81) | CA12CA1CA2CA7CA14 | |
| Sulfamate SCHEMBL285371 | 0.44 | — | — | |
| Sulfamate SCHEMBL11400 | 0.44 | — | — | |
| Sulfamide SCHEMBL27676226 | 0.44 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563761-A1 | ACTIVATORS OF HUMAN PYRUVATE KINASE | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2013-03-06 | — | — | EP | disclosed |