⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205711 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL28184536 | 0.76 | ING2 (0.31) | — | |
| SCHEMBL27578246 | 0.67 | CA1 (0.34) | — | |
| SCHEMBL27858841 | 0.59 | CA12 (0.31) | — | |
| SCHEMBL14734808 | 0.59 | CA12 (0.31) | — | |
| Sulfamate SCHEMBL16687154 | 0.57 | TSHR (0.55) | — | |
| SCHEMBL6227999 | 0.57 | — | — | |
| SCHEMBL28784628 | 0.56 | — | — | |
| SCHEMBL7406044 | 0.55 | — | — | |
| SCHEMBL202948 | 0.48 | CA2 (0.81) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3813832-A1 | COMPOUNDS FOR USE IN PREVENTING OR TREATING CANCER | Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (ES) | 2021-05-05 | — | — | EP | claimed |
| CN-109476594-A | Indoline derivatives and methods of use and preparation thereof | 亚利桑那大学董事会 | 2019-03-15 | — | — | CN | claimed |
| CN-105764895-A | Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy | 艾伯维德国有限责任两合公司 | 2016-07-13 | — | — | CN | claimed |
| CN-1882578-B | 2, 4-di (hetero) arylaminopyrimidine derivatives as ZAP-70 and/or SYK inhibitors | NOVARTIS AG | 2011-07-20 | — | — | CN | claimed |
| US-20240400502-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | UNIV QUEENSLAND (AU) | 2024-12-05 | — | — | US | disclosed |
| EP-4288412-A1 | MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | Rappta Therapeutics Oy (FI) | 2023-12-13 | — | — | EP | disclosed |
| CN-109071454-B | Sulfonylureas and related compounds and uses thereof | 昆士兰大学 | 2023-02-17 | — | — | CN | disclosed |
| CN-113582889-A | Sulfonylureas and related compounds and uses thereof | 昆士兰大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-113563264-A | Sulfonylureas and related compounds and uses thereof | 昆士兰大学 | 2021-10-29 | — | — | CN | disclosed |
| CN-107428696-B | Sulfonylureas and related compounds and uses thereof | 昆士兰大学 | 2021-08-20 | — | — | CN | disclosed |
| CN-109715629-A | AZA-INDAZOLE COMPOUNDS FOR USE IN TENDON AND/OR LIGAMENT INJURIES | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109476594-A | Indoline derivatives and methods of use and preparation thereof | 亚利桑那大学董事会 | 2019-03-15 | — | — | CN | disclosed |
| CN-105764895-A | Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy | 艾伯维德国有限责任两合公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-102260248-A | 2,4 DI (hetero) -arylamino-pyrimidine derivatives as zap-70 and/or syk inhibitors | — | 2011-11-30 | — | — | CN | disclosed |
| CN-1882578-B | 2, 4-di (hetero) arylaminopyrimidine derivatives as ZAP-70 and/or SYK inhibitors | NOVARTIS AG | 2011-07-20 | — | — | CN | disclosed |
| CN-100486973-C | Novel benzodioxoles | HOFFMANN LA ROCHE (CH) | 2009-05-13 | — | — | CN | disclosed |
| CN-1882578-A | 2, 4-di (hetero) arylaminopyrimidine derivatives as ZAP-70 and/or SYK inhibitors | NOVARTIS AG (CH) | 2006-12-20 | — | — | CN | disclosed |
| CN-1671684-A | New benzodioxoles | HOFFMANN LA ROCHE (CH) | 2005-09-21 | — | — | CN | disclosed |
| EP-1532132-A1 | NOVEL BENZODIOXOLES | F.HOFFMANN-LA ROCHE AG (CH) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004013120-A1 | NOVEL BENZODIOXOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-12 | — | — | WO | disclosed |