Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504173 | 0.93 | POLB (0.56) | TSHRMEN1KMT2APOLBMAOB | |
| SCHEMBL15498216 | 0.87 | KMT2A (0.45) | TSHRMEN1KMT2APOLBMAOB | |
| SCHEMBL14735379 | 0.86 | TSHR (0.49) | TSHRMEN1KMT2APOLBMAOB | |
| SCHEMBL1767329 | 0.84 | TSHR (0.65) | TSHRMEN1KMT2AMAOBMAOA | |
| SCHEMBL15743613 | 0.82 | ALDH1A1 (0.43) | TSHRMEN1KMT2APOLBMAOB | |
| SCHEMBL7861196 | 0.80 | TSHR (0.59) | TSHRMEN1KMT2AMAOBMAOA | |
| SCHEMBL18714233 | 0.78 | TSHR (0.57) | TSHRMEN1KMT2AMAOBMAOA | |
| SCHEMBL28381738 | 0.78 | TSHR (0.57) | TSHRMEN1KMT2AMAOBMAOA | |
| SCHEMBL11503161 | 0.78 | TSHR (0.67) | TSHRMEN1KMT2AMAOBMAOA | |
| SCHEMBL3721964 | 0.78 | TSHR (0.57) | TSHRMEN1KMT2AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563765-A1 | BICYCLIC COMPOUND DERIVATIVES AND THEIR USE AS ACC INHIBITORS. | Takeda Pharmaceutical Company Limited (JP) | 2013-03-06 | — | — | EP | disclosed |