SCHEMBL14735116

SCHEMBL14735116

O=C(CCc1ccccc1)N1CCC(O)(Cn2cnc3cc(Cl)ccc3c2=O)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30061726 0.95 USP7 (0.91) USP7
SCHEMBL20864451 0.95 USP7 (0.91) USP7
SCHEMBL20864351 0.92 USP7 (0.85) USP7
SCHEMBL20864296 0.91 USP7 (0.84) USP7
SCHEMBL20864340 0.91 USP7 (0.84) USP7
SCHEMBL20864300 0.91 USP7 (0.83) USP7
SCHEMBL30063698 0.91 USP7 (0.83) USP7
SCHEMBL20864305 0.91 USP7 (0.82) USP7
SCHEMBL20864318 0.91 USP7 (0.82) USP7
SCHEMBL20864353 0.91 USP7 (0.82) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117925814-A Use of USP-7 in the manufacture of a product for diagnosis or risk assessment of diabetic heart disease 广东药科大学 2024-04-26 CN claimed
US-9546150-B2 Substituted quinazolin-4-ones for inhibiting ubiquitin specific protease 7 HYBRIGENICS SA (FR) 2017-01-17 US claimed
EP-2751092-B1 SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 HYBRIGENICS SA (FR) 2016-07-27 EP claimed
US-20140371247-A1 Selective and Reversible Inhibitors of Ubiquitin Specific Protease 7 HYBRIGENICS SA (FR) 2014-12-18 US claimed
EP-2751092-A1 SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 Hybrigenics S.A. (FR) 2014-07-09 EP claimed
WO-2013030218-A1 SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 HYBRIGENICS SA (FR) 2013-03-07 WO claimed
EP-2565186-A1 Selective and reversible inhibitors of ubiquitin specific protease 7 Hybrigenics S.A. (FR) 2013-03-06 EP claimed
US-20260024617-A1 METHODS AND SYSTEMS FOR PERSONALIZED THERAPIES SCIPHER MEDICINE CORP (US) 2026-01-22 US disclosed
CN-118021824-B Medicine for resisting Marek's disease virus and application of dandelion sterol or ferulic acid in preparation of medicine by combination 吉林大学 2024-11-26 CN disclosed
CN-118021772-B Anti-Marek's disease virus medicine, resveratrol or chlorogenic acid and application of resveratrol or chlorogenic acid in combination in preparation of medicine 吉林大学 2024-11-08 CN disclosed
CN-118078824-B Anti-Marek's disease virus medicine and application of RA190 or glycyrrhizic acid and combined use thereof in preparation of medicine 吉林大学 2024-11-08 CN disclosed
CN-117925814-B Use of USP-7 in the manufacture of a product for diagnosis or risk assessment of diabetic heart disease 广东药科大学 2024-08-02 CN disclosed
US-20240203555-A1 METHODS AND SYSTEMS FOR THERAPY MONITORING AND TRIAL DESIGN SCIPHER MEDICINE CORP (US) 2024-06-20 US disclosed
US-9546150-B2 Substituted quinazolin-4-ones for inhibiting ubiquitin specific protease 7 HYBRIGENICS SA (FR) 2017-01-17 US disclosed
EP-2751092-B1 SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 HYBRIGENICS SA (FR) 2016-07-27 EP disclosed
US-20140371247-A1 Selective and Reversible Inhibitors of Ubiquitin Specific Protease 7 HYBRIGENICS SA (FR) 2014-12-18 US disclosed
US-20140371247-A1 Selective and Reversible Inhibitors of Ubiquitin Specific Protease 7 HYBRIGENICS SA (FR) 2014-12-18 US disclosed
US-20140371247-A1 Selective and Reversible Inhibitors of Ubiquitin Specific Protease 7 HYBRIGENICS SA (FR) 2014-12-18 US disclosed
WO-2013030218-A1 SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 HYBRIGENICS SA (FR) 2013-03-07 WO disclosed
EP-2565186-A1 Selective and reversible inhibitors of ubiquitin specific protease 7 Hybrigenics S.A. (FR) 2013-03-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260024617-A1 METHODS AND SYSTEMS FOR PERSONALIZED THERAPIES SET, SSB, CNKSR1 USP7 1137/4885
US-20140371247-A1 Selective and Reversible Inhibitors of Ubiquitin Specific Protease 7 USP7, UBA7, SENP7 USP7 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.