Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3075186 | 0.94 | CNR2 (0.47) | PHGDHSMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL27829814 | 0.89 | PHGDH (0.51) | PHGDHSMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL18362064 | 0.86 | PHGDH (0.52) | PHGDHSMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL19212256 | 0.85 | KMT2A (0.46) | SMN1; SMN2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL27927936 | 0.85 | ABL1 (0.44) | PHGDHSMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL27741480 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL21393062 | 0.84 | KMT2A (0.54) | PHGDHSMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL27927939 | 0.82 | KMT2A (0.47) | SMN1; SMN2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL20348529 | 0.82 | PHGDH (0.49) | PHGDHSMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL4098052 | 0.81 | KMT2A (0.44) | SMN1; SMN2KMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565182-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2013-03-06 | — | — | EP | disclosed |