SCHEMBL14735610

SCHEMBL14735610

CCCCCCCC(C)OC(=O)CNC(=O)Oc1ncccc1O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
FAAH O00519 6/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
NAAA Q02083 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14735535 0.88 MAPT (0.41) KDM4EKMT2AL3MBTL1FAAHCNR1
SCHEMBL7610436 0.83 EGLN2 (0.38) KMT2AL3MBTL1ALDH1A1MAPT
SCHEMBL1509110 0.83 EGLN2 (0.52) KDM4EKMT2AL3MBTL1FAAHCNR1
SCHEMBL7605070 0.83 KDM4E (0.47) KDM4EFAAHALDH1A1MAPT
SCHEMBL7614162 0.83 KDM4E (0.47) KDM4EFAAHALDH1A1MAPT
SCHEMBL7614301 0.83 KDM4E (0.47) KDM4EFAAHALDH1A1MAPT
SCHEMBL7612233 0.83 KDM4E (0.47) KDM4EFAAHALDH1A1MAPT
SCHEMBL7610580 0.83 KDM4E (0.47) KDM4EFAAHALDH1A1MAPT
SCHEMBL7609545 0.83 KDM4E (0.47) KDM4EFAAHALDH1A1MAPT
SCHEMBL7605129 0.83 KDM4E (0.47) KDM4EFAAHALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1463823-B1 METHODS OF INCREASING ENDOGENOUS ERYTHROPOIETIN (EPO) FIBROGEN INC (US) 2013-03-06 EP claimed