Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14735610 | 0.88 | KDM4E (0.41) | MAPTL3MBTL1KDM4EKMT2AFAAH | |
| SCHEMBL964845 | 0.85 | MAPT (0.43) | MAPTL3MBTL1KDM4EKMT2AFAAH | |
| SCHEMBL8374644 | 0.84 | TSHR (0.37) | MAPTL3MBTL1KDM4EKMT2AFAAH | |
| SCHEMBL8374350 | 0.84 | SMN1; SMN2 (0.39) | MAPTALDH1A1HTTLMNA | |
| SCHEMBL8378284 | 0.83 | FAAH (0.42) | L3MBTL1KDM4EKMT2AFAAHHTT | |
| SCHEMBL8374645 | 0.83 | FAAH (0.42) | L3MBTL1KDM4EKMT2AFAAHHTT | |
| SCHEMBL8377428 | 0.83 | FAAH (0.42) | L3MBTL1KDM4EKMT2AFAAHHTT | |
| SCHEMBL8374262 | 0.83 | FAAH (0.42) | L3MBTL1KDM4EKMT2AFAAHHTT | |
| SCHEMBL8378114 | 0.83 | FAAH (0.42) | L3MBTL1KDM4EKMT2AFAAHHTT | |
| SCHEMBL8808655 | 0.83 | FAAH (0.42) | L3MBTL1KDM4EKMT2AFAAHHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463823-B1 | METHODS OF INCREASING ENDOGENOUS ERYTHROPOIETIN (EPO) | FIBROGEN INC (US) | 2013-03-06 | — | — | EP | claimed |