Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 11/20 | 0.43 |
| ▸ | NPY2R | P49146 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APOB | P04114 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14735725 | 1.00 | MTTP (0.43) | MTTPNPY2RGAAPOLBAPOB | |
| Usistapide SCHEMBL785351 | 0.96 | NPY2R (0.47) | MTTPNPY2RGAAPOLBAPOB | |
| SCHEMBL785011 | 0.89 | GAA (0.41) | MTTPGAAPOLBAPOBMMP9 | |
| SCHEMBL786257 | 0.89 | GAA (0.41) | MTTPGAAPOLBAPOBMMP9 | |
| SCHEMBL904380 | 0.82 | MTTP (0.52) | MTTPNPY2RAPOB | |
| SCHEMBL904386 | 0.82 | MTTP (0.52) | MTTPNPY2RAPOB | |
| SCHEMBL904381 | 0.82 | MTTP (0.52) | MTTPNPY2RAPOB | |
| Hydrochloric Acid SCHEMBL2579600 | 0.81 | MTTP (0.51) | MTTPNPY2RAPOB | |
| SCHEMBL14748036 | 0.80 | NPY2R (0.51) | MTTPNPY2RGAAAPOBSMN1; SMN2 | |
| SCHEMBL14748023 | 0.80 | NPY2R (0.51) | MTTPNPY2RGAAAPOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435406-B1 | RESOLUTION OF (±)-METHYL PHENYL[4-[4-[[[4'-(TRIFLUOROMETHYL)-2-BIPHENYLYL]CARBONYL]AMINO]PHENYL]-1-PIPERIDINYL]ACETATE | JANSSEN PHARMACEUTICA NV (BE) | 2013-03-06 | — | — | EP | claimed |
| EP-2435406-B1 | RESOLUTION OF (±)-METHYL PHENYL[4-[4-[[[4'-(TRIFLUOROMETHYL)-2-BIPHENYLYL]CARBONYL]AMINO]PHENYL]-1-PIPERIDINYL]ACETATE | JANSSEN PHARMACEUTICA NV (BE) | 2013-03-06 | — | — | EP | disclosed |