Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.81 |
| ▸ | HTT | P42858 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.75 |
| ▸ | GAA | P10253 | 3/20 | 0.75 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | CA12 | O43570 | 3/20 | 0.70 |
| ▸ | CA1 | P00915 | 3/20 | 0.70 |
| ▸ | CA2 | P00918 | 3/20 | 0.70 |
| ▸ | CA9 | Q16790 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29345146 | 0.93 | LMNA (0.94) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL11810697 | 0.90 | LMNA (1.00) | LMNAHTTMAPTKMT2APOLB | |
| SCHEMBL14128251 | 0.87 | LMNA (0.83) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL23321396 | 0.86 | LMNA (0.82) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL1657522 | 0.86 | MAPT (0.87) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL29583869 | 0.86 | MAPT (0.87) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL14735692 | 0.86 | GBA1 (0.69) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL15613253 | 0.86 | GAA (1.00) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL30033818 | 0.85 | LMNA (0.75) | LMNAHTTMAPTKMT2AGAA | |
| SCHEMBL4623927 | 0.85 | LMNA (0.75) | LMNAHTTMAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101684115-A | 4-(5-((2-(4-morpholinyl-6-phenylamino group-1,3,5-triazine-2-base) hydrazono) methyl) furan-2-base) benzoic acid, preparing method and application thereof | SHANGHAI INST PHARM INDUSTRY | 2010-03-31 | — | — | CN | claimed |
| WO-2024191947-A1 | PIKFYVE INHIBITOR COMBINATION THERAPY | ORPHAI THERAPEUTICS INC. (US) | 2024-09-19 | — | — | WO | disclosed |
| WO-2024118515-A1 | PIKFYVE INHIBITOR COMBINATION THERAPY | ORPHAI THERAPEUTICS INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| WO-2024107448-A1 | APILIMOD COMBINATION THERAPY | ORPHAI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024015281-A1 | APILIMOD COMBINATION THERAPY | AI Therapeutics, Inc. (US) | 2024-01-18 | — | — | WO | disclosed |
| WO-2024015286-A1 | APILIMOD COMBINATION THERAPY | AI Therapeutics, Inc. (US) | 2024-01-18 | — | — | WO | disclosed |
| WO-2023196579-A9 | COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING A VIRAL INFECTION | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023196579-A1 | COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING A VIRAL INFECTION | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-10-12 | — | — | WO | disclosed |
| EP-2481731-B1 | Insecticidal (1,3,5)-triazinyl phenyl hydrazones | DOW AGROSCIENCES LLC (US) | 2013-10-23 | — | — | EP | disclosed |
| EP-2197857-B1 | INSECTICIDAL (1,3,5)-TRIAZINYL PHENYL HYDRAZONES | DOW AGROSCIENCES LLC (US) | 2013-03-06 | — | — | EP | disclosed |
| CN-101684115-B | 4-(5-((2-(4-morpholinyl-6-phenylamino group-1,3,5-triazine-2-base) hydrazono) methyl) furan-2-base) benzoic acid, preparing method and application thereof | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2011-12-21 | — | — | CN | disclosed |
| CN-101684115-A | 4-(5-((2-(4-morpholinyl-6-phenylamino group-1,3,5-triazine-2-base) hydrazono) methyl) furan-2-base) benzoic acid, preparing method and application thereof | SHANGHAI INST PHARM INDUSTRY | 2010-03-31 | — | — | CN | disclosed |