SCHEMBL4623927

SCHEMBL4623927

c1ccc(Nc2nc(NC(=C(Nc3nc(Nc4ccccc4)nc(N4CCOCC4)n3)c3ccccc3)c3ccccc3)nc(N3CCOCC3)n2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.75
HTT P42858 2/20 0.75
CA12 O43570 3/20 0.65
CA1 P00915 3/20 0.65
CA2 P00918 3/20 0.65
CA9 Q16790 3/20 0.65
POLB P06746 4/20 0.65
KMT2A Q03164 5/20 0.63
MEN1 O00255 2/20 0.63
MAPT P10636 4/20 0.60
SMN1; SMN2 Q16637 2/20 0.59
GAA P10253 2/20 0.59
TP53 P04637 1/20 0.58
PTGS2 P35354 1/20 0.57
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
TAAR1 Q96RJ0 1/20 0.55
NPSR1 Q6W5P4 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30033818 1.00 LMNA (0.75) LMNAHTTCA12CA1CA2
SCHEMBL29345146 0.89 LMNA (0.94) LMNAHTTCA12CA1CA2
SCHEMBL11810697 0.86 LMNA (1.00) LMNAHTTCA12CA1CA2
SCHEMBL14735802 0.85 LMNA (0.81) LMNAHTTCA12CA1CA2
SCHEMBL19210070 0.85 LMNA (0.64) LMNAHTTCA12CA1CA2
SCHEMBL11059702 0.85 LMNA (0.75) LMNAHTTCA12CA1CA2
SCHEMBL14128251 0.84 LMNA (0.83) LMNAHTTCA12CA1CA2
SCHEMBL29437100 0.83 CA12 (0.64) LMNAHTTCA12CA1CA2
SCHEMBL5190368 0.83 CA12 (0.64) LMNAHTTCA12CA1CA2
SCHEMBL5140588 0.82 CA12 (0.54) LMNAHTTCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862835-B2 Window coating WindowAlert, Inc. (US) 2018-01-09 US disclosed
US-20140037838-A1 WINDOW COATING WindowAlert, Inc. (US) 2014-02-06 US disclosed
EP-1904618-A1 A PACKAGED PRODUCT FOR MULTI-PHASE LAUNDRY TABLETS Unilever PLC (GB) 2008-04-02 EP disclosed
WO-2007025603-A1 A PACKAGED PRODUCT FOR MULTI-PHASE LAUNDRY TABLETS UNILEVER PLC (GB) 2007-03-08 WO disclosed
EP-1147171-B8 DETERGENT TABLETS UNILEVER PLC (GB) 2006-06-28 EP disclosed
EP-1456339-A1 PROCESS FOR PRODUCTION OF DETERGENT TABLETS UNILEVER N.V. (NL) 2004-09-15 EP disclosed
EP-1373456-A1 CLEANING TABLETS UNILEVER N.V. (NL) 2004-01-02 EP disclosed
EP-1358312-A1 CLEANING COMPOSITIONS UNILEVER N.V. (NL) 2003-11-05 EP disclosed
EP-1343866-A1 CLEANING COMPOSITIONS UNILEVER N.V. (NL) 2003-09-17 EP disclosed
EP-1335968-A1 CLEANING COMPOSITIONS UNILEVER N.V. (NL) 2003-08-20 EP disclosed
EP-1133549-A1 DETERGENT COMPOSITIONS UNILEVER PLC (GB) 2001-09-19 EP disclosed
WO-2001038479-A1 DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2001-05-31 WO disclosed
WO-2001038478-A1 DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2001-05-31 WO disclosed
WO-2000044869-A1 DETERGENT TABLETS UNILEVER PLC (GB) 2000-08-03 WO disclosed
WO-2000032741-A1 DETERGENT COMPOSITIONS UNILEVER PLC (GB) 2000-06-08 WO disclosed
US-6051545-A COMPACTED TABLET; MIXTURE OF SURFACTANT, BUILDER AND POLYMER LEVER BROTHERS COMPANY DIVISION OF CONOPCO, INC. (US) 2000-04-18 US disclosed
EP-0672104-B1 PROTECTION OF ADJUNCTS UNILEVER PLC (GB) 1997-07-02 EP disclosed
US-5480575-A IN A BIOPOLYMER; BLEACH CATALYSTS/PRECURSORS, BLEACH PRECURSORS; NON-AQUEOUS LIQUID DETERGENTS LEVER BROTHERS, DIVISION OF CONOPCO, INC. (US) 1996-01-02 US disclosed
EP-0672104-A1 PROTECTION OF ADJUNCTS. UNILEVER PLC (GB) 1995-09-20 EP disclosed
WO-1994012613-A1 PROTECTION OF ADJUNCTS UNILEVER PLC (GB) 1994-06-09 WO disclosed