Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14735731 | 0.89 | STAMBP (0.42) | MAPTGAASMN1; SMN2HPGDPOLB | |
| SCHEMBL8810151 | 0.89 | GAA (0.46) | MAPTGAASMN1; SMN2HPGDPOLB | |
| SCHEMBL8806156 | 0.86 | SMPD1 (0.45) | MAPTGAASMN1; SMN2HPGDKMT2A | |
| SCHEMBL8810909 | 0.86 | SMPD1 (0.45) | MAPTGAASMN1; SMN2HPGDKMT2A | |
| SCHEMBL8808599 | 0.86 | SMPD1 (0.45) | MAPTGAASMN1; SMN2HPGDKMT2A | |
| SCHEMBL8810764 | 0.86 | SMPD1 (0.45) | MAPTGAASMN1; SMN2HPGDKMT2A | |
| SCHEMBL1508960 | 0.86 | EGLN1 (0.53) | MAPTGAASMN1; SMN2HPGDPOLB | |
| SCHEMBL8807029 | 0.82 | GAA (0.42) | MAPTGAASMN1; SMN2HPGDPOLB | |
| SCHEMBL8811077 | 0.81 | GAA (0.41) | MAPTGAASMN1; SMN2HPGDPOLB | |
| SCHEMBL8784539 | 0.79 | GAA (0.45) | MAPTGAASMN1; SMN2TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463823-B1 | METHODS OF INCREASING ENDOGENOUS ERYTHROPOIETIN (EPO) | FIBROGEN INC (US) | 2013-03-06 | — | — | EP | claimed |