Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7133361 | 0.87 | ALDH1A1 (0.60) | CYP1A2TSHRALDH1A1TDP1MAPT | |
| SCHEMBL8808242 | 0.84 | CYP1A2 (0.55) | CYP1A2TSHRALDH1A1TDP1MAPT | |
| SCHEMBL7877336 | 0.84 | CYP1A2 (0.55) | CYP1A2TSHRALDH1A1TDP1MAPT | |
| SCHEMBL8808237 | 0.84 | CYP1A2 (0.55) | CYP1A2TSHRALDH1A1TDP1MAPT | |
| SCHEMBL27815461 | 0.83 | CYP1A2 (0.55) | CYP1A2TSHRALDH1A1MAPTMEN1 | |
| SCHEMBL14733944 | 0.82 | ALDH1A1 (0.55) | CYP1A2TSHRALDH1A1TDP1MAPT | |
| SCHEMBL16335086 | 0.80 | CYP1A2 (0.67) | CYP1A2TSHRALDH1A1TDP1MAPT | |
| SCHEMBL2598761 | 0.80 | CYP1A2 (0.67) | CYP1A2TSHRALDH1A1TDP1MAPT | |
| SCHEMBL16335088 | 0.80 | CYP1A2 (0.67) | CYP1A2TSHRALDH1A1TDP1MAPT | |
| SCHEMBL6605025 | 0.80 | CYP1A2 (0.67) | CYP1A2TSHRALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029723-A1 | NOVEL PHOTOACTIVATABLE PACLITAXEL DERIVATIVES AND USES THEREOF, IN PARTICULAR IN CELLBIOLOGY AND CANCER TREATMENT | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2013-03-07 | — | — | WO | claimed |
| EP-2565188-A1 | Novel photoactivatable paclitaxel derivatives and uses thereof, in particular in cellbiology and cancer treatment | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-03-06 | — | — | EP | claimed |
| WO-2013029723-A1 | NOVEL PHOTOACTIVATABLE PACLITAXEL DERIVATIVES AND USES THEREOF, IN PARTICULAR IN CELLBIOLOGY AND CANCER TREATMENT | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2013-03-07 | — | — | WO | disclosed |
| EP-2565188-A1 | Novel photoactivatable paclitaxel derivatives and uses thereof, in particular in cellbiology and cancer treatment | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-03-06 | — | — | EP | disclosed |
| EP-2565188-A1 | Novel photoactivatable paclitaxel derivatives and uses thereof, in particular in cellbiology and cancer treatment | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-03-06 | — | — | EP | disclosed |