Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733944 | 0.85 | ALDH1A1 (0.55) | CYP1A2ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL7133361 | 0.84 | ALDH1A1 (0.60) | CYP1A2ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL14735892 | 0.84 | CYP1A2 (0.61) | CYP1A2ALDH1A1TSHRTDP1HSD17B10 | |
| SCHEMBL12050502 | 0.83 | ALDH1A1 (0.58) | CYP1A2ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL27918543 | 0.83 | ALDH1A1 (0.58) | CYP1A2ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL7874932 | 0.82 | ALDH1A1 (0.51) | CYP1A2ALDH1A1TSHRCYP3A4THRB | |
| SCHEMBL8808237 | 0.82 | CYP1A2 (0.55) | CYP1A2ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL5583400 | 0.81 | ALDH1A1 (0.56) | CYP1A2ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL6895354 | 0.81 | ALDH1A1 (0.52) | CYP1A2ALDH1A1TSHRCYP3A4TDP1 | |
| SCHEMBL27815461 | 0.81 | CYP1A2 (0.55) | CYP1A2ALDH1A1TSHRL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026947-A1 | LIGHT-CONTROLLED ACTIVATION AND INTERNALISATION OF SMALL MOLECULES THAT CAN BIND TO DOUBLE-STRANDED DNA | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2013-02-28 | — | — | WO | disclosed |
| US-6310083-B1 | DERIVATIVES OF O-NITROMANDELYOXYCARBONYL WHICH ARE CAPABLE OF RELEASING AMINO ACIDS (OR DERIVATIVES THEREOF) UPON IRRADIATION WITH ULTRAVIOLET LIGHT; PRODUCING AMINO ACIDS (OR DERIVATIVES THEREOF) FOR USE IN NEUROPHYSIOLOGY STUDIES | UNIVERSITY OF MARYLAND BOITECHNOLOGY INSTITUTE | 2001-10-30 | — | — | US | disclosed |
| US-5635608-A | CONTAINS PHOTOREMOVABLE ALPHA-CARBOXY-SUBSTITUTED ORTHO-NITROBENZYL GROUP THAT CHANGES THE FLUORESCENCE AND BIOLOGICAL PROPERTIES OF THE COMPOUND | MOLECULAR PROBES, INC. (US) | 1997-06-03 | — | — | US | disclosed |