Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 4/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21817004 | 0.83 | KDM4E (0.48) | GABRA1GABRB2HTR1AHTR2CHTR2A | |
| SCHEMBL21817001 | 0.83 | KDM4E (0.48) | GABRA1GABRB2HTR1AHTR2CHTR2A | |
| SCHEMBL22500107 | 0.72 | ABCG2 (0.59) | ALOX5ALDH1A1SMN1; SMN2NFE2L2ABCG2 | |
| SCHEMBL22500105 | 0.72 | ABCG2 (0.59) | ALOX5ALDH1A1SMN1; SMN2NFE2L2ABCG2 | |
| SCHEMBL5505151 | 0.70 | CA12 (0.37) | LMNATDP1 | |
| SCHEMBL25328798 | 0.70 | KDM4E (0.41) | GABRA1GABRB2HTR1AHTR2CKDM4E | |
| SCHEMBL29150855 | 0.66 | APP (0.51) | GABRA1GABRB2ALOX5HTR1AHTR2C | |
| SCHEMBL647363 | 0.65 | KDM4E (0.40) | HTR1AHTR2CKDM4EALDH1A1HPGD | |
| SCHEMBL647361 | 0.65 | KDM4E (0.40) | HTR1AHTR2CKDM4EALDH1A1HPGD | |
| SCHEMBL942219 | 0.65 | CA12 (0.46) | GABRA1GABRB2HTR1AHTR2CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563845-A1 | NOVEL ORGANOPOLYSILOXANE, SURFACTANT, EMULSION COMPOSITION, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL-BASED RAW MATERIAL, GELLING AGENT, GEL COMPOSITION, AND COSMETIC RAW MATERIAL COMPRISING NOVEL ORGANOPOLYSILOXANE, AS WELL AS, PREPARATION FOR EXTERNAL USE AND COSMETIC COMPRISING THE SAME | Dow Corning Toray Co., Ltd. (JP) | 2013-03-06 | — | — | EP | disclosed |