SCHEMBL5505151

SCHEMBL5505151

COc1c(C=CC(=O)OO[Si](C)(C)C)cc(C([SiH3])CC(C)C)c(OC)c1OC

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
LMNA P02545 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL910611 0.73 MAP3K7 (0.39) CA12CA1CA2CA4CA6
SCHEMBL14735899 0.70 GABRA1 (0.37) LMNATDP1
SCHEMBL22500107 0.69 ABCG2 (0.59) LMNA
SCHEMBL22500105 0.69 ABCG2 (0.59) LMNA
SCHEMBL3986446 0.66 LMNA (0.33) LMNATDP1
SCHEMBL19177415 0.66 LMNA (0.33) LMNATDP1
SCHEMBL22070142 0.63 ALOX5 (0.37) LMNATDP1
SCHEMBL1402241 0.62 ABCG2 (0.47) CA12CA1CA2CA4CA6
SCHEMBL1402246 0.62 ABCG2 (0.47) CA12CA1CA2CA4CA6
SCHEMBL21625542 0.62 ALOX5 (0.39) LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113747875-A Composition containing ultraviolet wavelength converting substance 株式会社资生堂 2021-12-03 CN disclosed
WO-2019176124-A1 WATERPROOF-COATING FORMING AGENT 有限会社 日本健康科学研究センター 2019-09-19 WO disclosed
WO-2019176555-A1 COSMETIC 信越化学工業株式会社 2019-09-19 WO disclosed
EP-1847262-B1 COSMETIC SHINETSU CHEMICAL CO (JP) 2014-04-23 EP disclosed
EP-1847262-A1 COSMETIC Shiseido Company, Limited (JP) 2007-10-24 EP disclosed