Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 10/20 | 1.00 |
| ▸ | FBP1 | P09467 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14738959 | 0.91 | GPR17 (0.84) | GPR17FBP1KDM4EALDH1A1 | |
| SCHEMBL14739513 | 0.82 | GPR17 (0.70) | GPR17FBP1KDM4EALDH1A1 | |
| SCHEMBL14739871 | 0.82 | GPR17 (1.00) | GPR17FBP1KDM4EALDH1A1 | |
| SCHEMBL14739389 | 0.81 | GPR17 (1.00) | GPR17FBP1KDM4EALDH1A1 | |
| SCHEMBL14738966 | 0.81 | GPR17 (1.00) | GPR17FBP1KDM4EALDH1A1 | |
| SCHEMBL14739168 | 0.73 | GPR17 (1.00) | GPR17FBP1KDM4EALDH1A1 | |
| SCHEMBL14739118 | 0.72 | GPR17 (0.76) | GPR17FBP1KDM4EALDH1A1 | |
| SCHEMBL9188167 | 0.72 | GPR17 (0.67) | GPR17FBP1KDM4EALDH1A1 | |
| SCHEMBL29432490 | 0.71 | KDM4E (1.00) | GPR17KDM4EALDH1A1 | |
| SCHEMBL9188195 | 0.71 | KDM4E (1.00) | GPR17KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623593-B1 | GPR 17 agonists and screening assay | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2014-01-07 | — | — | US | claimed |
| US-20130338374-A1 | GPR 17 AGONISTS AND SCREENING ASSAY | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2013-12-19 | — | — | US | claimed |
| US-20130158093-A1 | GPR 17 Agonists and Screening Assay | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2013-06-20 | — | — | US | claimed |
| US-8404436-B1 | Methods of identifying modulators of GPR17 | RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (DE) | 2013-03-26 | — | — | US | claimed |
| US-20130059899-A1 | METHODS OF IDENTIFYING MODULATORS OF GPR17 | RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (DE) | 2013-03-07 | — | — | US | claimed |
| US-8623593-B1 | GPR 17 agonists and screening assay | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2014-01-07 | — | — | US | disclosed |
| US-8623593-B1 | GPR 17 agonists and screening assay | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2014-01-07 | — | — | US | disclosed |
| US-8623593-B1 | GPR 17 agonists and screening assay | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2014-01-07 | — | — | US | disclosed |
| US-20130338374-A1 | GPR 17 AGONISTS AND SCREENING ASSAY | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2013-12-19 | — | — | US | disclosed |
| US-20130158093-A1 | GPR 17 Agonists and Screening Assay | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130158093-A1 | GPR 17 Agonists and Screening Assay | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130158093-A1 | GPR 17 Agonists and Screening Assay | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2013-06-20 | — | — | US | disclosed |
| US-8404436-B1 | Methods of identifying modulators of GPR17 | RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (DE) | 2013-03-26 | — | — | US | disclosed |
| US-8404436-B1 | Methods of identifying modulators of GPR17 | RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (DE) | 2013-03-26 | — | — | US | disclosed |
| US-8404436-B1 | Methods of identifying modulators of GPR17 | RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (DE) | 2013-03-26 | — | — | US | disclosed |
| US-20130059899-A1 | METHODS OF IDENTIFYING MODULATORS OF GPR17 | RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (DE) | 2013-03-07 | — | — | US | disclosed |
| US-20130059899-A1 | METHODS OF IDENTIFYING MODULATORS OF GPR17 | RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN (DE) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059899-A1 | METHODS OF IDENTIFYING MODULATORS OF GPR17 | GPR27, GPR17, GPR65 | GPR17 2/4885FBP1 2790/4885KDM4E 3598/4885 |
| US-20130338374-A1 | GPR 17 AGONISTS AND SCREENING ASSAY | GPR27, GPR17, GPR65 | GPR17 2/4885FBP1 3381/4885KDM4E 4167/4885 |
| US-20130158093-A1 | GPR 17 Agonists and Screening Assay | GPR27, GPR17, GPR65 | GPR17 2/4885FBP1 3381/4885KDM4E 4167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.