Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20844809 | 0.97 | KIT (0.93) | KIT | |
| SCHEMBL14738588 | 0.97 | KIT (1.00) | KIT | |
| SCHEMBL14738218 | 0.97 | KIT (1.00) | KIT | |
| SCHEMBL14739898 | 0.95 | KIT (0.90) | KIT | |
| SCHEMBL21387471 | 0.94 | KIT (0.89) | KIT | |
| SCHEMBL20844776 | 0.94 | KIT (0.91) | KIT | |
| SCHEMBL14753335 | 0.94 | KIT (0.89) | KIT | |
| SCHEMBL14739910 | 0.93 | KIT (0.87) | KIT | |
| SCHEMBL27337264 | 0.93 | KIT (0.87) | KIT | |
| SCHEMBL21372452 | 0.93 | KIT (0.86) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751102-B1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | NOVARTIS AG (CH) | 2019-03-27 | — | — | EP | claimed |
| US-9199981-B2 | Compounds and compositions as C-kit kinase inhibitors | NOVARTIS AG (CH) | 2015-12-01 | — | — | US | claimed |
| EP-2751102-A1 | COMPOUNDS AND COMPOSITIONS AS c-KIT KINASE INHIBITORS | IRM LLC (BM) | 2014-07-09 | — | — | EP | claimed |
| WO-2013033070-A1 | COMPOUNDS AND COMPOSITIONS AS c-KIT KINASE INHIBITORS | IRM LLC (BM) | 2013-03-07 | — | — | WO | claimed |
| US-20130059846-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | IRM LLC (BM) | 2013-03-07 | — | — | US | claimed |
| US-11767319-B2 | Crystalline forms of a selective c-kit kinase inhibitor | THIRD HARMONIC BIO, INC. (US) | 2023-09-26 | — | — | US | disclosed |
| WO-2022109595-A1 | PHARMACEUTICAL COMPOSITIONS OF A SELECTIVE C-KIT KINASE INHIBITOR AND METHODS FOR MAKING AND USING SAME | THIRD HARMONIC BIO, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022106615-A1 | PHARMACEUTICAL COMPOSITIONS OF A SELECTIVE C-KIT KINASE INHIBITOR AND METHODS FOR MAKING AND USING SAME | NOVARTIS AG (CH) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022016021-A1 | CRYSTALLINE FORMS OF A SELECTIVE C-KIT KINASE INHIBITOR | THIRD HARMONIC BIO, INC. (US) | 2022-01-20 | — | — | WO | disclosed |
| WO-2020228746-A1 | CRYSTALLINE FORMS OF N- (5- (5- ( (1R, 2S) -2-FLUOROCYCLOPROPYL) -1, 2, 4-OXADIAZOL-3-YL) -2-METHYLPHENYL) IMIDAZO [1, 2-A] PYRIDINE-3-CARBOXAMIDE | NOVARTIS AG (CH) | 2020-11-19 | — | — | WO | disclosed |
| EP-2751102-B1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | NOVARTIS AG (CH) | 2019-03-27 | — | — | EP | disclosed |
| EP-2751102-B1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | NOVARTIS AG (CH) | 2019-03-27 | — | — | EP | disclosed |
| US-9199981-B2 | Compounds and compositions as C-kit kinase inhibitors | NOVARTIS AG (CH) | 2015-12-01 | — | — | US | disclosed |
| US-9199981-B2 | Compounds and compositions as C-kit kinase inhibitors | NOVARTIS AG (CH) | 2015-12-01 | — | — | US | disclosed |
| EP-2751102-A1 | COMPOUNDS AND COMPOSITIONS AS c-KIT KINASE INHIBITORS | IRM LLC (BM) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013033070-A1 | COMPOUNDS AND COMPOSITIONS AS c-KIT KINASE INHIBITORS | IRM LLC (BM) | 2013-03-07 | — | — | WO | disclosed |
| WO-2013033070-A1 | COMPOUNDS AND COMPOSITIONS AS c-KIT KINASE INHIBITORS | IRM LLC (BM) | 2013-03-07 | — | — | WO | disclosed |
| US-20130059846-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | IRM LLC (BM) | 2013-03-07 | — | — | US | disclosed |
| US-20130059846-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | IRM LLC (BM) | 2013-03-07 | — | — | US | disclosed |
| US-20130059846-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | IRM LLC (BM) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767319-B2 | Crystalline forms of a selective c-kit kinase inhibitor | KIT, PRKACA, PRKDC | KIT 1/4885 |
| US-20130059846-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | KIT, PDGFRA, PDGFRB | KIT 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.