SCHEMBL21372452

SCHEMBL21372452

Cc1ccc(-c2noc(C3CCN(C(=O)O)CC3)n2)cc1NC(=O)c1cnc2ccccn12

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIT P10721 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21372437 0.95 KIT (0.81) KIT
SCHEMBL14740017 0.94 KIT (0.86) KIT
SCHEMBL14740096 0.93 KIT (0.85) KIT
SCHEMBL14739173 0.93 KIT (1.00) KIT
SCHEMBL14741957 0.92 KIT (0.83) KIT
SCHEMBL21387471 0.92 KIT (0.89) KIT
SCHEMBL21372447 0.92 KIT (0.83) KIT
SCHEMBL14740176 0.92 KIT (0.83) KIT
SCHEMBL14739659 0.92 KIT (0.83) KIT
SCHEMBL20844809 0.91 KIT (0.93) KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2751104-B1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS NOVARTIS AG (CH) 2019-09-25 EP claimed