SCHEMBL14739323

SCHEMBL14739323

CCC=CCC=CCC=CCC=CCC=CCCCC(=O)NCCSSCCNC(=O)CCCC(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 4/20 0.64
▸ KMT2A Q03164 4/20 0.64
▸ MAPT P10636 4/20 0.64
▸ MEN1 O00255 3/20 0.64
▸ SLC6A5 Q9Y345 2/20 0.64
▸ ALDH1A1 P00352 7/20 0.63
▸ F7 P08709 3/20 0.63
▸ CYP19A1 P11511 3/20 0.63
▸ F3 P13726 3/20 0.63
▸ PTGS1 P23219 3/20 0.63
▸ PPARG P37231 2/20 0.63
▸ PPARD Q03181 2/20 0.63
▸ PPARA Q07869 2/20 0.63
▸ OXER1 Q8TDS5 2/20 0.63
▸ ADORA3 P0DMS8 1/20 0.63
▸ RXRA P19793 1/20 0.63
▸ KDM4E B2RXH2 3/20 0.59
▸ CYP3A4 P08684 2/20 0.56
▸ HPGD P15428 2/20 0.56
▸ ALOX15 P16050 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14739321 1.00 CNR1 (0.64) CNR1KMT2AMAPTMEN1SLC6A5
SCHEMBL14740182 0.95 CNR1 (0.64) CNR1KMT2AMAPTMEN1SLC6A5
SCHEMBL14740184 0.95 CNR1 (0.64) CNR1KMT2AMAPTMEN1SLC6A5
SCHEMBL14739223 0.95 ALDH1A1 (0.59) CNR1KMT2AMAPTMEN1SLC6A5
SCHEMBL14739222 0.95 ALDH1A1 (0.59) CNR1KMT2AMAPTMEN1SLC6A5
SCHEMBL12478623 0.93 CNR1 (0.73) CNR1KMT2AMAPTMEN1ALDH1A1
SCHEMBL1604481 0.91 CNR1 (0.66) CNR1KMT2AMAPTMEN1SLC6A5
SCHEMBL14739704 0.91 CNR1 (0.66) CNR1KMT2AMAPTMEN1SLC6A5
SCHEMBL12685101 0.91 CNR1 (0.69) CNR1KMT2AMAPTMEN1ALDH1A1
SCHEMBL14752451 0.89 CNR1 (0.68) CNR1KMT2AMAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130059801-A1 FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE CATABASIS PHARMACEUTICALS, INC. (US) 2013-03-07 — — US claimed
US-20170073305-A1 FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE CATABASIS PHARMACEUTICALS, INC. 2017-03-16 — — US disclosed
US-20130059801-A1 FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE CATABASIS PHARMACEUTICALS, INC. (US) 2013-03-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059801-A1 FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE FASN, FADS1, ELOVL5 CNR1 1072/4885KMT2A 1112/4885MAPT 234/4885
US-20170073305-A1 FATTY ACID AMIDES, COMPOSITIONS AND METHODS OF USE FASN, FADS1, ELOVL5 CNR1 1072/4885KMT2A 1112/4885MAPT 234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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