Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16835454 | 0.86 | SMN1; SMN2 (0.63) | HTTTDP1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL829571 | 0.84 | NCEH1 (0.51) | HTTTDP1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10293626 | 0.80 | HTT (0.86) | HTTKDM4EHRH4ALDH1A1GAA | |
| SCHEMBL14740658 | 0.79 | ALDH1A1 (0.60) | HTTTDP1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL18297996 | 0.79 | SMN1; SMN2 (0.76) | HTTTDP1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10471511 | 0.78 | TP53 (0.53) | TDP1KDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL21089037 | 0.78 | TP53 (0.51) | HTTTDP1KDM4EHRH4ALDH1A1 | |
| SCHEMBL14740641 | 0.78 | TP53 (0.55) | HTTALDH1A1GAASMN1; SMN2TP53 | |
| SCHEMBL10459212 | 0.77 | GAA (0.66) | KDM4EALDH1A1GAASMN1; SMN2TP53 | |
| SCHEMBL9460569 | 0.75 | ALDH1A1 (0.54) | KDM4EALDH1A1GAASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033250-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2013-03-07 | — | — | WO | claimed |