Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10053020 | 0.94 | MAPT (0.60) | ALDH1A1POLBMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL27723918 | 0.85 | ALDH1A1 (0.82) | ALDH1A1POLBMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL2297216 | 0.81 | KMT2A (0.53) | ALDH1A1POLBMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL2297217 | 0.81 | KMT2A (0.53) | ALDH1A1POLBMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL15134826 | 0.81 | CYP1A2 (0.69) | ALDH1A1POLBMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL1735264 | 0.80 | ALDH1A1 (0.56) | ALDH1A1POLBMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL5646336 | 0.80 | LIPE (0.61) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL14740655 | 0.79 | HTT (0.55) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL5104855 | 0.79 | GAA (0.66) | ALDH1A1POLBNPSR1SMN1; SMN2NPC1 | |
| SCHEMBL8747161 | 0.78 | ALDH1A1 (0.79) | ALDH1A1POLBMAPTNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033250-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2013-03-07 | — | — | WO | claimed |