Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | NR1I3 | Q14994 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14740339 | 0.74 | DPP4 (0.46) | DPP4NR1I3KDM4EPOLBHSD17B10 | |
| SCHEMBL14740051 | 0.73 | NR1I3 (0.43) | DPP4NR1I3KDM4EALDH1A1HPGD | |
| SCHEMBL14740209 | 0.73 | DPP4 (0.43) | DPP4NR1I3KDM4EALDH1A1HPGD | |
| SCHEMBL14739603 | 0.73 | NR1I3 (0.42) | DPP4NR1I3KDM4EALDH1A1HPGD | |
| SCHEMBL14739456 | 0.72 | NR1I3 (0.52) | DPP4NR1I3NR1I2 | |
| SCHEMBL14740348 | 0.72 | ALDH1A1 (0.53) | DPP4NR1I3KDM4EALDH1A1HPGD | |
| SCHEMBL14739346 | 0.71 | NR1I3 (0.43) | DPP4NR1I3KDM4EALDH1A1HPGD | |
| SCHEMBL14740266 | 0.71 | DPP4 (0.42) | DPP4NR1I3KDM4EALDH1A1HPGD | |
| SCHEMBL14740335 | 0.71 | LMNA (0.46) | DPP4NR1I3KDM4EALDH1A1POLB | |
| SCHEMBL14740387 | 0.71 | DPP4 (0.42) | DPP4NR1I3KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013032939-A1 | BICYCLIC AGONISTS OF GPR131 AND USES THEREOF | METABOLEX, INC. (US) | 2013-03-07 | — | — | WO | disclosed |