Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1472000 | 0.84 | FAAH (0.53) | FAAHCES1 | |
| SCHEMBL1471784 | 0.82 | FAAH (0.50) | FAAH | |
| SCHEMBL1471482 | 0.82 | FAAH (0.57) | FAAHCES1 | |
| SCHEMBL1471185 | 0.82 | FAAH (0.49) | FAAH | |
| SCHEMBL1471331 | 0.82 | FAAH (0.50) | FAAH | |
| SCHEMBL1471729 | 0.81 | FAAH (0.53) | FAAHCES1HDAC3HDAC4HDAC1 | |
| SCHEMBL1471868 | 0.80 | FAAH (0.52) | FAAH | |
| SCHEMBL17104340 | 0.79 | FAAH (0.54) | FAAH | |
| SCHEMBL1471172 | 0.79 | FAAH (0.59) | FAAHCES1 | |
| SCHEMBL1472142 | 0.79 | FAAH (0.55) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1983994-B1 | OXAZOLE KETONES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2015-09-30 | — | — | EP | disclosed |
| US-7915270-B2 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-03-29 | — | — | US | disclosed |
| EP-1983994-A2 | OXAZOLE KETONES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | The Scripps Research Institute (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007098142-A2 | OXAZOLE KETONES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-08-30 | — | — | WO | disclosed |
| US-20070203156-A1 | Oxazole ketones as modulators of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203156-A1 | Oxazole ketones as modulators of fatty acid amide hydrolase | FAAH, FAAH2, HCRTR2 | FAAH 1/4885CES1 81/4885HDAC3 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.