Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743329 | 0.92 | NPC1 (0.45) | NPC1RAB9AMEN1KMT2ABCL2A1 | |
| SCHEMBL14743730 | 0.90 | PTGES (0.55) | NPC1RAB9AMEN1KMT2ALPAR1 | |
| SCHEMBL14743655 | 0.90 | TSHR (0.42) | NPC1MEN1KMT2APDK1PTGES | |
| SCHEMBL14743067 | 0.85 | ALDH1A1 (0.43) | NPC1RAB9AMEN1KMT2APDK1 | |
| SCHEMBL14743568 | 0.83 | MRGPRX4 (0.36) | NPC1RAB9AMEN1KMT2APTGES | |
| SCHEMBL14743539 | 0.83 | PTGES (0.48) | NPC1RAB9ALPAR1LPAR5TAS2R14 | |
| SCHEMBL14743558 | 0.82 | ALDH1A1 (0.45) | MEN1KMT2ATSHR | |
| SCHEMBL14743729 | 0.80 | PTGES (0.47) | MEN1KMT2ATAS2R14PTGESALOX5 | |
| SCHEMBL14743619 | 0.80 | ALDH1A1 (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL14743090 | 0.80 | MEN1 (0.43) | RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |