Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | USP8 | P40818 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744345 | 0.78 | RORC (0.45) | RORCARALDH1A1KDM4EADORA2A | |
| SCHEMBL17266575 | 0.72 | LRRK2 (0.49) | ESR2ARALDH1A1KDM4EADORA2A | |
| SCHEMBL27909137 | 0.72 | ESR2 (0.52) | ESR2ALDH1A1KDM4EUSP8USP7 | |
| SCHEMBL3259923 | 0.72 | CYP1A2 (0.47) | ESR2ALDH1A1KDM4EADORA2AUSP8 | |
| SCHEMBL14744241 | 0.72 | PLA2G7 (0.55) | ALDH1A1KDM4EGABRG2GABRB3GABRA5 | |
| SCHEMBL16013714 | 0.72 | CYP3A4 (0.39) | ALDH1A1KDM4EADORA2AADORA1CYP3A4 | |
| SCHEMBL38650555 | 0.72 | CYP1A1 (0.42) | ALDH1A1ADORA2AHPGDMAPTPOLB | |
| SCHEMBL22664353 | 0.71 | RORC (0.36) | RORCARALDH1A1KDM4EHPGD | |
| SCHEMBL222 | 0.71 | ESR2 (0.60) | ESR2ARALDH1A1KDM4EUSP8 | |
| SCHEMBL29412287 | 0.71 | ESR2 (0.60) | ESR2ARALDH1A1KDM4EUSP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |