Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.65 |
| ▸ | RORB | Q92753 | 2/20 | 0.54 |
| ▸ | RORA | P35398 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744538 | 0.83 | RORC (0.60) | RORCRORBRORA | |
| SCHEMBL14744404 | 0.82 | RORC (0.70) | RORC | |
| SCHEMBL14746785 | 0.81 | RORC (0.67) | RORCRORBNR1I2 | |
| SCHEMBL14746619 | 0.79 | RORC (1.00) | RORC | |
| SCHEMBL14746793 | 0.78 | RORC (0.61) | RORC | |
| SCHEMBL14744377 | 0.78 | RORC (0.84) | RORC | |
| SCHEMBL14744339 | 0.77 | RORC (0.71) | RORC | |
| SCHEMBL14744550 | 0.76 | RORC (0.62) | RORC | |
| SCHEMBL14746652 | 0.76 | RORC (1.00) | RORC | |
| SCHEMBL14746749 | 0.76 | RORC (0.69) | RORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |