Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744540 | 0.89 | MEN1 (0.68) | RORCMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL14744339 | 0.88 | RORC (0.71) | RORC | |
| SCHEMBL14744550 | 0.86 | RORC (0.62) | RORCKMT2A | |
| SCHEMBL14744554 | 0.85 | RORC (0.62) | RORC | |
| SCHEMBL14746366 | 0.83 | RORC (0.58) | RORC | |
| SCHEMBL14746619 | 0.82 | RORC (1.00) | RORC | |
| SCHEMBL14744174 | 0.82 | RORC (0.73) | RORC | |
| SCHEMBL14744474 | 0.82 | RORC (0.71) | RORCMEN1LMNAKMT2A | |
| SCHEMBL14744221 | 0.82 | RORC (0.65) | RORC | |
| SCHEMBL23174348 | 0.81 | RORC (0.89) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |