Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14754204 | 0.91 | RORC (0.62) | RORC | |
| SCHEMBL14754269 | 0.91 | RORC (0.69) | RORC | |
| SCHEMBL14754218 | 0.90 | RORC (0.75) | RORC | |
| SCHEMBL14743947 | 0.90 | RORC (0.54) | RORCBRD4CA12CA1CA2 | |
| SCHEMBL14754233 | 0.82 | RORC (0.68) | RORC | |
| SCHEMBL14746727 | 0.81 | RORC (0.81) | RORC | |
| SCHEMBL14754236 | 0.81 | RORC (0.45) | RORC | |
| SCHEMBL14754186 | 0.81 | RORC (0.63) | RORC | |
| SCHEMBL24032696 | 0.81 | RORC (0.84) | RORC | |
| SCHEMBL30320951 | 0.81 | RORC (0.84) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |