Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.45 |
| ▸ | WNT3A | P56704 | 5/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14754267 | 0.91 | RORC (0.55) | RORC | |
| SCHEMBL14754204 | 0.82 | RORC (0.62) | RORCNR3C2 | |
| SCHEMBL14744222 | 0.81 | RORC (0.64) | RORC | |
| SCHEMBL14743947 | 0.79 | RORC (0.54) | RORCNR3C2 | |
| SCHEMBL14754205 | 0.78 | RORC (0.72) | RORC | |
| SCHEMBL14746709 | 0.78 | RORC (0.60) | RORC | |
| SCHEMBL14743966 | 0.74 | RAB9A (0.54) | RORC | |
| SCHEMBL14747104 | 0.74 | RORC (0.54) | RORC | |
| SCHEMBL14754233 | 0.74 | RORC (0.68) | RORC | |
| SCHEMBL14754269 | 0.73 | RORC (0.69) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |