Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPR3 | P17342 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16012641 | 1.00 | FPR2 (0.39) | FPR2SCN9ACTSKLMNANPR3 | |
| SCHEMBL16013019 | 0.88 | FPR2 (0.39) | FPR2SCN9ACTSKNPR3 | |
| SCHEMBL14743768 | 0.88 | FPR2 (0.39) | FPR2SCN9ACTSKNPR3 | |
| SCHEMBL14742612 | 0.82 | LMNA (0.50) | FPR2SCN9ALMNA | |
| SCHEMBL14743791 | 0.82 | LMNA (0.50) | FPR2SCN9ALMNA | |
| SCHEMBL14744286 | 0.79 | SCN9A (0.59) | FPR2SCN9A | |
| SCHEMBL14744287 | 0.79 | SCN9A (0.59) | FPR2SCN9A | |
| SCHEMBL14743330 | 0.77 | SCN9A (0.71) | FPR2SCN9A | |
| SCHEMBL14744013 | 0.77 | SCN9A (0.71) | FPR2SCN9A | |
| SCHEMBL14743097 | 0.76 | SCN9A (0.59) | FPR2SCN9ALMNANPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030665-A1 | PYRIMIDINES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA L.P. (US) | 2013-03-07 | — | — | WO | disclosed |