Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360452 | 0.89 | L3MBTL1 (0.59) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL641210 | 0.87 | HPGD (0.63) | MEN1KMT2AMAPTHPGDEPAS1 | |
| SCHEMBL3845633 | 0.84 | MEN1 (0.67) | MEN1KMT2AMAPTHPGDEPAS1 | |
| SCHEMBL9688249 | 0.83 | MAPT (0.58) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL6748077 | 0.82 | MAPT (0.62) | MEN1KMT2AMAPTHPGDEPAS1 | |
| SCHEMBL641831 | 0.82 | HPGD (0.65) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL28219324 | 0.81 | L3MBTL1 (0.62) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL238962 | 0.81 | L3MBTL1 (0.62) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL7126645 | 0.81 | L3MBTL1 (0.51) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL9131558 | 0.81 | L3MBTL1 (0.51) | MEN1KMT2AMAPTHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |