SCHEMBL238962

SCHEMBL238962

O=[N+]([O-])c1ccccc1Oc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.62
HPGD P15428 1/20 0.62
ALDH1A1 P00352 4/20 0.60
TDP1 Q9NUW8 3/20 0.60
RECQL P46063 2/20 0.58
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
KMT2A Q03164 4/20 0.57
MEN1 O00255 3/20 0.57
TTR P02766 1/20 0.57
ALB P02768 1/20 0.57
THRB P10828 1/20 0.57
LTA4H P09960 1/20 0.55
PTGS1 P23219 1/20 0.55
PTGS2 P35354 1/20 0.55
ESR2 Q92731 1/20 0.54
TLR4 O00206 1/20 0.53
TLR2 O60603 1/20 0.53
HPSE Q9Y251 1/20 0.52
HTT P42858 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10944795 0.89 L3MBTL1 (0.56) L3MBTL1HPGDALDH1A1TDP1RECQL
SCHEMBL10360452 0.89 L3MBTL1 (0.59) L3MBTL1HPGDALDH1A1TDP1RECQL
SCHEMBL28219324 0.88 L3MBTL1 (0.62) L3MBTL1HPGDALDH1A1TDP1RECQL
SCHEMBL39472 0.87 HPGD (0.78) L3MBTL1HPGDALDH1A1TDP1RECQL
SCHEMBL1283885 0.87 HSPB1 (0.67) L3MBTL1HPGDALDH1A1TDP1RECQL
2,4'-Oxybis(Nitrobenzene) SCHEMBL9474586 0.87 HSPB1 (0.62) L3MBTL1HPGDALDH1A1TDP1RECQL
SCHEMBL6750951 0.87 L3MBTL1 (0.57) L3MBTL1HPGDALDH1A1TDP1RECQL
SCHEMBL7123876 0.85 L3MBTL1 (0.56) L3MBTL1HPGDALDH1A1TDP1RECQL
SCHEMBL641831 0.85 HPGD (0.65) L3MBTL1HPGDALDH1A1TDP1RECQL
SCHEMBL7010633 0.85 L3MBTL1 (0.56) L3MBTL1HPGDALDH1A1TDP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 498 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110918107-A Medicine intermediate 2-phenoxyaniline and preparation method thereof 南京卡邦科技有限公司 2020-03-27 CN claimed
US-7732534-B2 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2010-06-08 US claimed
US-20080051519-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2008-02-28 US claimed
US-20080051552-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION 2008-02-28 US claimed
EP-0807382-B1 Synergistic herbicidal agents BAYER CROPSCIENCE GMBH (DE) 2005-06-08 EP claimed
US-6864217-B2 Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice HOECHST SCHERING AGREVO GMBH (DE) 2005-03-08 US claimed
US-20030191025-A1 Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-10-09 US claimed
EP-1096855-A1 HERBICIDES WITH SUBSTITUTED PHENYLSULFONYLUREAS FOR CONTROLLING WEEDS IN RICE Aventis CropScience GmbH (DE) 2001-05-09 EP claimed
EP-0713646-B1 Synergistic herbicidal agents AVENTIS CROPSCIENCE GMBH (DE) 2000-05-03 EP claimed
EP-0807381-B1 Synergistic herbicidal agents HOECHST SCHERING AGREVO GMBH (DE) 2000-03-15 EP claimed
US-5298502-A Exposure to light in presence of oxidase inhibitor FMC CORPORATION (US) 1994-03-29 US claimed
EP-0525474-A2 Synergistic herbicidal agents Hoechst Schering AgrEvo GmbH (DE) 1993-02-03 EP claimed
EP-0482491-A2 Synergistic herbicidal agents HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-29 EP claimed
WO-1991019418-A1 TREATMENT OF DISEASE FMC CORPORATION (US) 1991-12-26 WO claimed
US-5045107-A From herbicides, plant safening agents CIBA-GEIGY CORPORATION (US) 1991-09-03 US claimed
EP-0055693-B1 USE OF PHENYL PYRIMIDINES AS PROTECTING AGENTS FOR CULTURE PLANTS AGAINST PHYTOTOXIC DAMAGE CAUSED BY HERBICIDES CIBA-GEIGY AG (CH) 1988-01-20 EP claimed
EP-0130370-B1 PROCESS FOR PREPARING LIQUID PLANT-PROTECTION AGENT COMBINATIONS HOECHST AKTIENGESELLSCHAFT (DE) 1987-11-25 EP claimed
US-4511729-A Nucleophilic substitution process ETHYL CORPORATION (US) 1985-04-16 US claimed
US-4502998-A Nucleophilic substitution process ETHYL CORPORATION (US) 1985-03-05 US claimed
EP-0074198-A1 Hydrogen ion-selective membranes and electrodes containing same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-03-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191025-A1 Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice DDT, CYCS, CBR3 L3MBTL1 311/4885HPGD 4558/4885ALDH1A1 988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.