Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746593 | 0.82 | HSD17B10 (0.45) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL10405791 | 0.80 | HSD17B10 (0.72) | MAPTCYP3A4ALDH1A1LMNAKMT2A | |
| SCHEMBL14746480 | 0.80 | HSD17B10 (0.53) | MAPTCYP1A2CYP3A4ALDH1A1RORC | |
| SCHEMBL8866265 | 0.79 | HTT (0.50) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL512092 | 0.79 | MAPT (0.67) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL29435299 | 0.79 | MAPT (0.67) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL8866256 | 0.78 | HTT (0.49) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL12114840 | 0.78 | RORC (0.54) | MAPTSMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL57125 | 0.77 | HTT (0.68) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL8866338 | 0.77 | ALPL (0.53) | MAPTSMN1; SMN2HPGDNPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |