Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665987 | 0.89 | KMT2A (0.53) | ALDH1A1LMNAKDM4ETSHRHSD17B10 | |
| SCHEMBL20709277 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4EHSD17B10GAA | |
| SCHEMBL165901 | 0.79 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4ETSHRHSD17B10 | |
| SCHEMBL2665972 | 0.78 | KMT2A (0.57) | ALDH1A1LMNAKDM4ETSHRHSD17B10 | |
| SCHEMBL27450030 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAGAACYP2C9KMT2A | |
| SCHEMBL5542953 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4ETSHRGAA | |
| SCHEMBL2400474 | 0.77 | KMT2A (0.51) | ALDH1A1TSHRGAACYP1A2CYP2C9 | |
| SCHEMBL1885468 | 0.77 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4ETSHRHSD17B10 | |
| SCHEMBL11038201 | 0.76 | CYP1A2 (0.47) | ALDH1A1LMNAKDM4ETSHRGAA | |
| SCHEMBL13481189 | 0.76 | KLK7 (0.52) | ALDH1A1KDM4EHSD17B10GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |