Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26071414 | 0.85 | TDP1 (0.52) | ALDH1A1MAPTTDP1TSHRMAPK1 | |
| SCHEMBL30490230 | 0.82 | TDP1 (0.57) | ALDH1A1TDP1TSHRMAPK1ATM | |
| SCHEMBL8013048 | 0.82 | TDP1 (0.57) | ALDH1A1TDP1TSHRMAPK1ATM | |
| SCHEMBL10996737 | 0.80 | TDP1 (0.67) | ALDH1A1MAPTTDP1TSHRMAPK1 | |
| SCHEMBL29793298 | 0.80 | MAPT (0.56) | ALDH1A1MAPTTDP1TSHRMAPK1 | |
| SCHEMBL27557557 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTTDP1TSHRMAPK1 | |
| SCHEMBL306584 | 0.80 | TDP1 (0.67) | ALDH1A1TDP1TSHRMAPK1ATM | |
| SCHEMBL632916 | 0.80 | MAPT (0.56) | ALDH1A1MAPTTDP1TSHRMAPK1 | |
| SCHEMBL29417506 | 0.80 | TDP1 (0.67) | ALDH1A1TDP1TSHRMAPK1ATM | |
| SCHEMBL25247609 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTTDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |