Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.43 |
| ▸ | MAP2 | P11137 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320910 | 0.86 | RORC (0.50) | RORCMAP2CYP2C9CYP2C19 | |
| SCHEMBL14744202 | 0.86 | RORC (0.50) | RORCMAP2CYP2C9CYP2C19 | |
| SCHEMBL14744529 | 0.86 | ALOX5AP (0.40) | RORCSLC22A12MAP2AR | |
| SCHEMBL14744191 | 0.81 | RORC (0.44) | RORCMAP2CYP2C9CYP2C19 | |
| SCHEMBL14744242 | 0.80 | RORC (0.48) | RORCMAP2CYP2C9CYP2C19 | |
| SCHEMBL28898212 | 0.80 | RORC (0.50) | RORCSLC22A12CYP2C9CYP2C19 | |
| SCHEMBL14746783 | 0.79 | KDM4E (0.43) | SLC22A12AR | |
| SCHEMBL14744245 | 0.74 | RORC (0.45) | RORCMAP2 | |
| SCHEMBL30321020 | 0.74 | RORC (0.45) | RORCMAP2 | |
| SCHEMBL14744380 | 0.73 | ALOX5AP (0.47) | RORCMAP2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522634-B | Biaryl urea carboxylic acid derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2020-09-01 | — | — | CN | disclosed |
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |