Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746854 | 0.83 | KDM4E (0.41) | DAOKDM4EALDH1A1 | |
| SCHEMBL14744741 | 0.80 | GRIN2D (0.30) | DAO | |
| SCHEMBL14745614 | 0.79 | DAO (0.39) | DAOKDM4EALDH1A1 | |
| SCHEMBL14745385 | 0.79 | DAO (0.41) | DAOKDM4EALDH1A1 | |
| SCHEMBL14746133 | 0.77 | GPR84 (0.39) | DAOKDM4E | |
| SCHEMBL14746849 | 0.77 | GPR84 (0.39) | DAOKDM4EALDH1A1 | |
| SCHEMBL16428129 | 0.76 | CA2 (0.43) | ALDH1A1 | |
| SCHEMBL14746103 | 0.75 | DAO (0.35) | DAOKDM4EALDH1A1CACNA1BAPBA1 | |
| SCHEMBL16428798 | 0.70 | MEN1 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL16567889 | 0.67 | CYP1A2 (0.36) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2750504-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC Therapeutics, Inc. (US) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013033258-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2013-03-07 | — | — | WO | disclosed |