Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL20550793 | 0.94 | POLB (0.47) | POLBSMN1; SMN2L3MBTL1KMT2AMAPT | |
| SCHEMBL8479931 | 0.88 | POLB (0.43) | POLBSMN1; SMN2L3MBTL1KMT2AMAPT | |
| SCHEMBL12277549 | 0.82 | POLB (0.63) | POLBNUDT1ROCK1HRH4AURKA | |
| SCHEMBL11853970 | 0.79 | POLB (0.47) | POLBNUDT1RAB9AROCK1HRH4 | |
| SCHEMBL2751610 | 0.78 | SMN1; SMN2 (0.46) | POLBSMN1; SMN2L3MBTL1KMT2AMAPT | |
| SCHEMBL83993 | 0.77 | POLB (0.56) | POLBNUDT1ROCK1HRH4AURKA | |
| SCHEMBL29718738 | 0.77 | POLB (0.56) | POLBNUDT1ROCK1HRH4AURKA | |
| SCHEMBL14215338 | 0.76 | SMN1; SMN2 (0.49) | POLBSMN1; SMN2L3MBTL1KMT2AMAPT | |
| SCHEMBL4978265 | 0.76 | SMN1; SMN2 (0.45) | POLBSMN1; SMN2L3MBTL1KMT2AMAPT | |
| SCHEMBL3275866 | 0.76 | SMN1; SMN2 (0.45) | POLBSMN1; SMN2L3MBTL1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108033916-B | Preparation of amino acid ester compound and application of amino acid ester compound in preventing and treating tobacco diseases | 贵州理工学院 | 2021-02-26 | — | — | CN | claimed |
| CN-102675219-A | Preparation method of 5-bromo-2-amino-4-dimethoxymethylpyrimidine | CGENE TECH SUZHOU CHINA CO LTD | 2012-09-19 | — | — | CN | claimed |
| EP-3619204-B1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | TIANLI BIOTECH PTY LTD (AU) | 2025-10-01 | — | — | EP | disclosed |
| US-20220380343-A1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | TIANLI BIOTECH PTY LTD (AU) | 2022-12-01 | — | — | US | disclosed |
| CN-108349896-B | Heterocyclic compounds as FGFR inhibitors | 南京天印健华医药科技有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-108033916-B | Preparation of amino acid ester compound and application of amino acid ester compound in preventing and treating tobacco diseases | 贵州理工学院 | 2021-02-26 | — | — | CN | disclosed |
| CN-108033916-B | Preparation of amino acid ester compound and application of amino acid ester compound in preventing and treating tobacco diseases | 贵州理工学院 | 2021-02-26 | — | — | CN | disclosed |
| US-10590109-B2 | Heterocyclic compounds used as FGFR inhibitors | NANJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2020-03-17 | — | — | US | disclosed |
| US-10590109-B2 | Heterocyclic compounds used as FGFR inhibitors | NANJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2020-03-17 | — | — | US | disclosed |
| US-20200079757-A1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | THE UNIVERSITY OF MELBOURNE (AU) | 2020-03-12 | — | — | US | disclosed |
| EP-3619204-A1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | The University of Melbourne (AU) | 2020-03-11 | — | — | EP | disclosed |
| US-5658903-A | Imidazole compounds, compositions and use | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0727998-A4 | OXAZOLES FOR TREATING CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORP (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5593992-A | CYTOKINE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| US-5593991-A | ANTIINFLAMMATORY, CYTOKINE INHIBITOR, CYCLOOXYGENASE INHIBITOR | SMITHKLINE BEECHAM CORPORATION | 1997-01-14 | — | — | US | disclosed |
| WO-1996040143-A1 | IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
| EP-0727998-A1 | OXAZOLES FOR TREATING CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-28 | — | — | EP | disclosed |
| WO-1996021452-A1 | CERTAIN 1,4,5-TRI-SUBSTITUTED IMIDAZOLE COMPOUNDS USEFUL AS CYTOKINE | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-18 | — | — | WO | disclosed |
| WO-1996021654-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-18 | — | — | WO | disclosed |
| WO-1995013067-A1 | OXAZOLES FOR TREATING CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10590109-B2 | Heterocyclic compounds used as FGFR inhibitors | FGFR1, FGFR3, FGFR2 | POLB 3498/4885SMN1; SMN2 2539/4885L3MBTL1 4492/4885 |
| US-20220380343-A1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | LTC4S, LTB4R2, LTB4R | POLB 1332/4885SMN1; SMN2 3328/4885L3MBTL1 4117/4885 |
| US-20200079757-A1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | LTC4S, LTB4R2, LTB4R | POLB 1332/4885SMN1; SMN2 3328/4885L3MBTL1 4117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.