Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | ESR1 | P03372 | 7/20 | 0.85 |
| ▸ | LMNA | P02545 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.79 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.79 |
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.78 |
| ▸ | ATM | Q13315 | 3/20 | 0.78 |
| ▸ | PGR | P06401 | 3/20 | 0.78 |
| ▸ | AR | P10275 | 3/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.78 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.78 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14094308 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL29616163 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL17302844 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL29351015 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL12449418 | 0.92 | ESR1 (1.00) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL2232043 | 0.92 | ESR1 (1.00) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL5033759 | 0.91 | MAPT (0.82) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL3299315 | 0.90 | MAPT (0.81) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL8155723 | 0.90 | MAPT (0.81) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL20885240 | 0.89 | SMN1; SMN2 (0.80) | MAPTSMN1; SMN2CYP3A4TP53ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3993856-A1 | AEROSOL DELIVERY DEVICES AND METHODS OF USING SAME | Airja, Inc. (US) | 2022-05-11 | — | — | EP | claimed |
| WO-2021003438-A1 | AEROSOL DELIVERY DEVICES AND METHODS OF USING SAME | AIRJA, INC. (US) | 2021-01-07 | — | — | WO | claimed |
| US-9782419-B2 | Transdermal contraceptive hormones delivery | AGILE THERAPEUTICS, INC. (US) | 2017-10-10 | — | — | US | claimed |
| US-9775817-B2 | Transdermal contraceptive hormones delivery | AGILE THERAPEUTICS, INC. (US) | 2017-10-03 | — | — | US | claimed |
| US-9775847-B2 | Transdermal contraceptive hormones delivery | AGILE THERAPEUTICS, INC. (US) | 2017-10-03 | — | — | US | claimed |
| US-9775848-B2 | Transdermal contraceptive hormones delivery | AGILE THERAPEUTICS, INC. (US) | 2017-10-03 | — | — | US | claimed |
| US-20170087099-A1 | TRANSDERMAL SYSTEMS CONTAINING MULTILAYER ADHESIVE MATRICES TO MODIFY DRUG DELIVERY | MYLAN TECH INC (US) | 2017-03-30 | — | — | US | claimed |
| EP-2608829-A2 | SYSTEMS AND METHODS OF AEROSOL DELIVERY WITH AIRFLOW REGULATION | Rubin, Darren (US) | 2013-07-03 | — | — | EP | claimed |
| WO-2012026963-A2 | SYSTEMS AND METHODS OF AEROSOL DELIVERY WITH AIRFLOW REGULATION | RUBIN DARREN (US) | 2012-03-01 | — | — | WO | claimed |
| US-20070287688-A1 | Pharmaceutical Compositions for Topical Application | MACRO CHEM CORPORATION | 2007-12-13 | — | — | US | claimed |
| WO-2007092085-A2 | FRAGRANCED THERAPEUTIC DELIVERY SYSTEM | MURAD HOWARD (US) | 2007-08-16 | — | — | WO | claimed |
| EP-1809240-A2 | CARDIAC SAFE, RAPID MEDICATION DELIVERY | Alexza Pharmaceuticals, Inc. (US) | 2007-07-25 | — | — | EP | claimed |
| US-7090830-B2 | Drug condensation aerosols and kits | ALEXZA PHARMACEUTICALS, INC. (US) | 2006-08-15 | — | — | US | claimed |
| US-20060120962-A1 | Cardiac safe, rapid medication delivery | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-06-08 | — | — | US | claimed |
| WO-2006044421-A2 | CARDIAC SAFE, RAPID MEDICATION DELIVERY | ALEXZA PHARMACEUTICALS, INC. (US) | 2006-04-27 | — | — | WO | claimed |
| EP-1648364-A2 | PHARMACEUTICAL COMPOSITIONS FOR TOPICAL APPLICATION | MacroChem Corporation (US) | 2006-04-26 | — | — | EP | claimed |
| WO-2005007100-A2 | PHARMACEUTICAL COMPOSITIONS FOR TOPICAL APPLICATION | MACROCHEM CORPORATION (US) | 2005-01-27 | — | — | WO | claimed |
| US-20040099269-A1 | Drug condensation aerosols and kits | ALEXZA MOLECULAR DELIVERY CORPORATION (US) | 2004-05-27 | — | — | US | claimed |
| EP-0269696-B1 | TRANSDERMAL ABSORPTION DOSAGE UNIT FOR ESTRADIOL AND OTHER ESTROGENIC STEROIDS | UNIV RUTGERS (US) | 1994-08-03 | — | — | EP | claimed |
| US-4346709-A | Drug delivery devices comprising erodible polymer and erosion rate modifier | ALZA CORPORATION (US) | 1982-08-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287688-A1 | Pharmaceutical Compositions for Topical Application | CYP8B1, NR1H3, NR1H2 | MAPT 3668/4885SMN1; SMN2 3027/4885CYP3A4 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.