Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.85 |
| ▸ | TP53 | P04637 | 4/20 | 0.85 |
| ▸ | LMNA | P02545 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.79 |
| ▸ | RECQL | P46063 | 2/20 | 0.79 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | STS | P08842 | 3/20 | 0.67 |
| ▸ | PGR | P06401 | 3/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.66 |
| ▸ | AR | P10275 | 3/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12449418 | 1.00 | ESR1 (1.00) | ESR1MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL17302844 | 0.92 | MAPT (1.00) | ESR1MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL14094308 | 0.92 | MAPT (1.00) | ESR1MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL29616163 | 0.92 | MAPT (1.00) | ESR1MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL29351015 | 0.92 | MAPT (1.00) | ESR1MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL147461 | 0.92 | MAPT (1.00) | ESR1MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL147037 | 0.89 | LMNA (1.00) | ESR1MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL13177178 | 0.89 | LMNA (1.00) | ESR1MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL8991456 | 0.89 | LMNA (1.00) | ESR1MAPTCYP3A4SMN1; SMN2TP53 | |
| SCHEMBL8643294 | 0.89 | LMNA (1.00) | ESR1MAPTCYP3A4SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831144-B1 | A NEW PROCESS FOR THE PREPARATION OF PHENOLIC HYDROXY-SUBSTITUTED COMPOUNDS | RICHTER GEDEON NYRT (HU) | 2011-08-17 | — | — | EP | claimed |
| US-7973185-B2 | Process for the preparation of phenolic hydroxy-substituted compounds | RICHTER GEDEON NYRT. (HU) | 2011-07-05 | — | — | US | claimed |
| US-20080039643-A1 | Process for the Preparation of Phenolic Hydroxy-Substituted Compounds | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-02-14 | — | — | US | claimed |
| EP-1831144-A2 | A NEW PROCESS FOR THE PREPARATION OF PHENOLIC HYDROXY-SUBSTITUTED COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2007-09-12 | — | — | EP | claimed |
| WO-2006061666-A2 | A NEW PROCESS FOR THE PREPARATION OF PHENOLIC HYDROXY-SUBSTITUTED COMPOUNDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-06-15 | — | — | WO | claimed |
| EP-1831144-B1 | A NEW PROCESS FOR THE PREPARATION OF PHENOLIC HYDROXY-SUBSTITUTED COMPOUNDS | RICHTER GEDEON NYRT (HU) | 2011-08-17 | — | — | EP | disclosed |
| US-7973185-B2 | Process for the preparation of phenolic hydroxy-substituted compounds | RICHTER GEDEON NYRT. (HU) | 2011-07-05 | — | — | US | disclosed |
| US-20080039643-A1 | Process for the Preparation of Phenolic Hydroxy-Substituted Compounds | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-02-14 | — | — | US | disclosed |
| EP-1831144-A2 | A NEW PROCESS FOR THE PREPARATION OF PHENOLIC HYDROXY-SUBSTITUTED COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006061666-A2 | A NEW PROCESS FOR THE PREPARATION OF PHENOLIC HYDROXY-SUBSTITUTED COMPOUNDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-06-15 | — | — | WO | disclosed |
| US-4029648-A | Process of making gona-1,3,5(10),9(11)-tetraenes | VEB JENAPHARM (DL) | 1977-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039643-A1 | Process for the Preparation of Phenolic Hydroxy-Substituted Compounds | NR3C2, CYP21A2, NR5A1 | ESR1 8/4885MAPT 4563/4885CYP3A4 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.