Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | ESR1 | P03372 | 7/20 | 0.85 |
| ▸ | LMNA | P02545 | 7/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.79 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.79 |
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.78 |
| ▸ | ATM | Q13315 | 3/20 | 0.78 |
| ▸ | PGR | P06401 | 3/20 | 0.78 |
| ▸ | AR | P10275 | 3/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.78 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.78 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14094308 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL147461 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL17302844 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL29351015 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL12449418 | 0.92 | ESR1 (1.00) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL2232043 | 0.92 | ESR1 (1.00) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL5033759 | 0.91 | MAPT (0.82) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL3299315 | 0.90 | MAPT (0.81) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL8155723 | 0.90 | MAPT (0.81) | MAPTSMN1; SMN2CYP3A4TP53ESR1 | |
| SCHEMBL20885240 | 0.89 | SMN1; SMN2 (0.80) | MAPTSMN1; SMN2CYP3A4TP53ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088928-A | Process for preparing high-purity estetrol | 湖北共同甾体药物研究院有限公司 | 2023-11-21 | — | — | CN | disclosed |