Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14754751 | 0.88 | PDE5A (0.49) | PDE5A | |
| SCHEMBL19480647 | 0.88 | PDE5A (0.59) | PDE5A | |
| SCHEMBL14746629 | 0.86 | PDE5A (0.53) | PDE5A | |
| SCHEMBL14746119 | 0.86 | GUCY1A1 (0.53) | PDE5A | |
| SCHEMBL15120888 | 0.77 | PDE5A (1.00) | PDE5A | |
| SCHEMBL15120887 | 0.73 | PDE5A (1.00) | PDE5A | |
| SCHEMBL15120980 | 0.71 | PDE5A (1.00) | PDE5A | |
| SCHEMBL3575506 | 0.71 | L3MBTL1 (0.42) | — | |
| SCHEMBL3579101 | 0.70 | NPC1 (0.41) | — | |
| SCHEMBL14776476 | 0.70 | GUCY1A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751106-A1 | SUBSTITUTED ANNELLATED PYRIMIDINE AND THE USE THEREOF | Bayer Intellectual Property GmbH (DE) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013030288-A1 | SUBSTITUTED ANNELLATED PYRIMIDINE AND THE USE THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-03-07 | — | — | WO | disclosed |