Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744550 | 0.84 | RORC (0.62) | RORC | |
| SCHEMBL14744554 | 0.83 | RORC (0.62) | RORC | |
| SCHEMBL14744404 | 0.83 | RORC (0.70) | RORC | |
| SCHEMBL14744174 | 0.81 | RORC (0.73) | RORC | |
| SCHEMBL14744474 | 0.80 | RORC (0.71) | RORC | |
| SCHEMBL14754199 | 0.80 | RORC (0.83) | RORC | |
| SCHEMBL14744070 | 0.80 | RORC (0.77) | RORC | |
| SCHEMBL29732523 | 0.78 | GRM4 (0.56) | — | |
| SCHEMBL22549232 | 0.78 | GRM4 (0.56) | — | |
| SCHEMBL14746793 | 0.78 | RORC (0.61) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |