Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Mepenzolate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 12/20 | 1.00 |
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.76 |
| ▸ | CHRM2 | P08172 | 11/20 | 1.00 |
| ▸ | SLC22A1 | O15245 | 1/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.97 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.97 |
| ▸ | LMNA | P02545 | 2/20 | 0.97 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.97 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.97 |
| ▸ | RAB9A | P51151 | 1/20 | 0.78 |
| ▸ | HRH1 | P35367 | 3/20 | 0.76 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.65 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mepenzolate SCHEMBL15575981 | 1.00 | CHRM3 (1.00) | CHRM3CHRM2SLC22A1KCNH2CYP2D6 | |
| Mepenzolate SCHEMBL15575855 | 1.00 | CHRM3 (1.00) | CHRM3CHRM2SLC22A1KCNH2CYP2D6 | |
| Mepenzolate SCHEMBL99030 | 1.00 | CHRM3 (1.00) | CHRM3CHRM2SLC22A1KCNH2CYP2D6 | |
| Mepenzolate SCHEMBL17008166 | 1.00 | CHRM3 (1.00) | CHRM3CHRM2SLC22A1KCNH2CYP2D6 | |
| Mepenzolate SCHEMBL15865414 | 0.99 | CHRM3 (0.97) | CHRM3CHRM2SLC22A1KCNH2CYP2D6 | |
| Mepenzolate SCHEMBL9441937 | 0.99 | CHRM3 (0.97) | CHRM3CHRM2SLC22A1KCNH2CYP2D6 | |
| Mepenzolate SCHEMBL3401786 | 0.99 | CHRM3 (0.97) | CHRM3CHRM2SLC22A1KCNH2CYP2D6 | |
| Mepenzolate SCHEMBL19411950 | 0.99 | CHRM3 (0.97) | CHRM3CHRM2SLC22A1KCNH2CYP2D6 | |
| Mepenzolate SCHEMBL2994933 | 0.99 | CHRM3 (1.00) | CHRM3CHRM2SLC22A1KCNH2CYP2D6 | |
| Mepenzolate SCHEMBL17071946 | 0.99 | CHRM3 (1.00) | CHRM3CHRM2SLC22A1KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5891 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4327374-A1 | PIEZOELECTRIC ACCELEROMETER WITH WAKE FUNCTION | Qualcomm Technologies, Inc. (US) | 2024-02-28 | — | — | EP | claimed |
| EP-4319816-A1 | ANTI-VENOM ANTIBODIES AND USES THEREOF | Centivax, Inc. (US) | 2024-02-14 | — | — | EP | claimed |
| CN-117370422-A | Verifiable traceability query method oriented to multi-chain environment | 东北大学 | 2024-01-09 | — | — | CN | claimed |
| CN-113628189-B | Rapid strip steel scratch defect detection method based on image recognition | 西安工程大学 | 2023-10-24 | — | — | CN | claimed |
| EP-4256778-A1 | NEIGHBORHOOD-GATED SWITCHING PIXEL SENSOR | VoxelSensors SRL (BE) | 2023-10-11 | — | — | EP | claimed |
| EP-4244673-A1 | MULTI-CAMERA HEAD-MOUNTED DEVICE | Iristick nv (BE) | 2023-09-20 | — | — | EP | claimed |
| CN-116542910-A | Stamping part round hole positioning and deformation detection method based on sub-pixel edge extraction | 福州大学 | 2023-08-04 | — | — | CN | claimed |
| CN-116009870-A | Verilog HDL code generation method for convolutional neural network state machine | 山东海量信息技术研究院 | 2023-04-25 | — | — | CN | claimed |
| CN-115599353-A | Applet development method, device, equipment and storage medium | 星河智联汽车科技有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-114791935-A | Method for realizing high-performance multidimensional data warehouse based on cloud object storage | 胡劲松 | 2022-07-26 | — | — | CN | claimed |
| US-4254629-A | FRACTIONAL DISTILLATION OF LIQUEFIED AIR USING LOW ENERGY; HIGH AND LOW PRESSURES | UNION CARBIDE CORPORATION (US) | 1981-03-10 | — | — | US | claimed |
| WO-1981000296-A1 | APPARATUS AND METHOD FOR PROCESSING ORGANIC MATERIALS | DEPEW T (US) | 1981-02-05 | — | — | WO | claimed |
| US-4181995-A | Modular structure for bridges, overpasses and roadways | KLEINBAUM, LIORA | 1980-01-08 | — | — | US | claimed |
| WO-1979001152-A1 | IMPROVEMENTS IN MODULAR BUILDING STRUCTURES | KUMP E (GB) | 1979-12-27 | — | — | WO | claimed |
| EP-0005378-A2 | Chlorination of hydrocarbons | KLIPFONTEIN ORGANIC PRODUCTS CORPORATION LIMITED (ZA) | 1979-11-14 | — | — | EP | claimed |
| EP-0001681-A1 | Dehydration of alcohols, preferably ethanol, using a cyclohexane entrainer | BP Chemicals Limited (GB) | 1979-05-02 | — | — | EP | claimed |
| US-4142858-A | USING DIVINYLBENZENE-METHACRYLIC ACID COPOLYMER ION EXCHANGER | ISOLAB, INCORPORATED (US) | 1979-03-06 | — | — | US | claimed |
| US-4020348-A | Gantry scanning camera | G. D. SEARLE & CO. (US) | 1977-04-26 | — | — | US | claimed |
| US-4011441-A | Solid state imaging apparatus | GENERAL ELECTRIC COMPANY (US) | 1977-03-08 | — | — | US | claimed |
| US-3944021-A | Emergency escape mechanism | Smith, Jr., Melvin F. | 1976-03-16 | — | — | US | claimed |