Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 17/20 | 0.63 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14747164 | 1.00 | NR1D1 (0.63) | NR1D1ACE | |
| SCHEMBL16889050 | 0.84 | NR1D1 (0.53) | NR1D1 | |
| SCHEMBL382552 | 0.82 | ACE (0.52) | NR1D1ACE | |
| SCHEMBL14740846 | 0.82 | NR1D1 (0.70) | NR1D1 | |
| SCHEMBL7532707 | 0.82 | NR1D1 (0.55) | NR1D1ACE | |
| SCHEMBL7532710 | 0.82 | NR1D1 (0.55) | NR1D1ACE | |
| SCHEMBL14744595 | 0.81 | NR1D1 (0.71) | NR1D1 | |
| SCHEMBL14744748 | 0.81 | NR1D1 (0.71) | NR1D1 | |
| SCHEMBL14744639 | 0.80 | NR1D1 (0.70) | NR1D1 | |
| SCHEMBL16889079 | 0.80 | NR1D1 (0.70) | NR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033310-A1 | MODULATORS OF REV-ERB | KAMENECKA THEODORE MARK (US) | 2013-03-07 | — | — | WO | disclosed |