Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 2/20 | 0.47 |
| ▸ | GJA1 | P17302 | 1/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027889 | 0.85 | GJB2 (0.51) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL5027888 | 0.85 | GJB2 (0.51) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL20010200 | 0.84 | HTR1A (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL18896703 | 0.84 | HTR1A (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL21283070 | 0.84 | HTR1A (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL23744216 | 0.84 | HTR1A (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL20404663 | 0.84 | HTR1A (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL1262772 | 0.84 | HTR1A (0.52) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL17267497 | 0.84 | GJB2 (0.46) | GJB2GJA1SSTR1SSTR2SSTR4 | |
| SCHEMBL17267495 | 0.84 | GJB2 (0.46) | GJB2GJA1SSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |