Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12998034 | 0.86 | ALDH1A1 (0.49) | ALDH1A1RAB9AMAPK14TSHRNPC1 | |
| SCHEMBL13688102 | 0.82 | RAB9A (0.54) | ALDH1A1RAB9AHTTMAPK14NPC1 | |
| SCHEMBL18134653 | 0.81 | RAB9A (0.61) | ALDH1A1RAB9ATSHRNPC1PKM | |
| SCHEMBL71048 | 0.77 | ALDH1A1 (0.56) | ALDH1A1RAB9ANPC1PKMGAA | |
| SCHEMBL13055154 | 0.76 | ALDH1A1 (0.47) | ALDH1A1RAB9AMAPK14TSHRNPC1 | |
| SCHEMBL13688122 | 0.75 | RAB9A (0.57) | ALDH1A1RAB9AHTTMAPK14TSHR | |
| SCHEMBL14946275 | 0.75 | RAB9A (0.51) | ALDH1A1RAB9AHTTNPC1HSD17B10 | |
| SCHEMBL33206 | 0.74 | RAB9A (0.56) | ALDH1A1RAB9AHTTTSHRNPC1 | |
| SCHEMBL13688142 | 0.74 | RAB9A (0.57) | ALDH1A1RAB9AHTTTSHRNPC1 | |
| SCHEMBL12998027 | 0.72 | TDP1 (0.48) | ALDH1A1RAB9ANPC1PKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123265-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2013-05-16 | — | — | US | disclosed |
| US-8389567-B2 | Compounds that modulate intracellular calcium | CALCIMEDICA, INC. (US) | 2013-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123265-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, ATP2A1 | ALDH1A1 4373/4885RAB9A 1003/4885HTT 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.