Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 2/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14838203 | 0.93 | LMNA (0.40) | LMNAMEN1USP2POLBKMT2A | |
| SCHEMBL14413572 | 0.91 | PTPN1 (0.51) | LMNAMEN1USP2POLBKMT2A | |
| SCHEMBL17850338 | 0.87 | PTPN1 (0.49) | LMNAMEN1USP2POLBKMT2A | |
| SCHEMBL26822757 | 0.87 | PTPN1 (0.49) | LMNAMEN1USP2POLBKMT2A | |
| SCHEMBL14725505 | 0.86 | LMNA (0.43) | LMNAMEN1USP2POLBKMT2A | |
| SCHEMBL19473210 | 0.86 | USP2 (0.40) | MEN1USP2POLBKMT2APTPN1 | |
| SCHEMBL19473211 | 0.86 | MEN1 (0.40) | LMNAMEN1USP2POLBKMT2A | |
| SCHEMBL16559639 | 0.86 | MEN1 (0.40) | MEN1USP2POLBKMT2APTPN1 | |
| SCHEMBL15833434 | 0.86 | PTPN1 (0.48) | LMNAMEN1USP2POLBKMT2A | |
| SCHEMBL16299427 | 0.86 | PTPN1 (0.48) | LMNAMEN1USP2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |