Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 8/20 | 0.47 |
| ▸ | GJB2 | P29033 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 2/20 | 0.41 |
| ▸ | SI | P14410 | 2/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.40 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16126909 | 0.92 | LGALS8 (0.52) | LGALS8TNFMAPK1GBA1LGALS3 | |
| SCHEMBL19678110 | 0.91 | GJB2 (0.52) | LGALS8GJB2TNFMAPK1GBA1 | |
| SCHEMBL19682033 | 0.90 | GBA1 (0.54) | LGALS8GJB2TNFMAPK1GBA1 | |
| SCHEMBL22390606 | 0.90 | GBA1 (0.54) | LGALS8GJB2TNFMAPK1GBA1 | |
| SCHEMBL19678117 | 0.90 | GBA1 (0.54) | LGALS8GJB2TNFMAPK1GBA1 | |
| SCHEMBL22390598 | 0.90 | GBA1 (0.54) | LGALS8GJB2TNFMAPK1GBA1 | |
| SCHEMBL22390602 | 0.90 | GBA1 (0.54) | LGALS8GJB2TNFMAPK1GBA1 | |
| SCHEMBL22404764 | 0.90 | GBA1 (0.54) | LGALS8GJB2TNFMAPK1GBA1 | |
| SCHEMBL19678120 | 0.90 | GBA1 (0.54) | LGALS8GJB2TNFMAPK1GBA1 | |
| SCHEMBL17857935 | 0.90 | GBA1 (0.54) | LGALS8GJB2TNFMAPK1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |